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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL221718
Molecular formula	C27H31F3N2O4
IUPAC name	2-[2-[4-[1-(2-ethoxyethyl)-6-(trifluoromethyl)indol-3-yl]piperidin-1-yl]ethoxy]benzoic acid
Molecular weight	504.55
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	2.5
Synonyms	BDBM50156895 2-(2-(4-(1-(2-ethoxyethyl)-6-(trifluoromethyl)-1H-indol-3-yl)piperidin-1-yl)ethoxy)benzoic acid
Inchi Key	CDOSJOMPTRDTHQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H31F3N2O4/c1-2-35-15-14-32-18-23(21-8-7-20(17-24(21)32)27(28,29)30)19-9-11-31(12-10-19)13-16-36-25-6-4-3-5-22(25)26(33)34/h3-8,17-19H,2,9-16H2,1H3,(H,33,34)
PubChem CID	11443495
ChEMBL	CHEMBL221718
IUPHAR	N/A
BindingDB	50156895
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
39477	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
39478	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359

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