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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL62269
Molecular formula	C25H27N7O3
IUPAC name	2-[2,6-dioxo-4-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pyrimidin-1-yl]-N,N-dimethylacetamide
Molecular weight	473.537
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.4
Synonyms	BDBM50285171 2-{2,6-Dioxo-4-propyl-3-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,6-dihydro-2H-pyrimidin-1-yl}-N,N-dimethyl-acetamide
Inchi Key	CBTOFFZALGYFNR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H27N7O3/c1-4-7-19-14-22(33)32(16-23(34)30(2)3)25(35)31(19)15-17-10-12-18(13-11-17)20-8-5-6-9-21(20)24-26-28-29-27-24/h5-6,8-14H,4,7,15-16H2,1-3H3,(H,26,27,28,29)
PubChem CID	10457566
ChEMBL	CHEMBL62269
IUPHAR	N/A
BindingDB	50285171
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
38199	Type-1 angiotensin II receptor	P25104	AGTR1	Bos taurus (Bovine)	359
38200	Type-1B angiotensin II receptor	P29089	Agtr1b	Rattus norvegicus (Rat)	359

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