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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1357034
Molecular formula	C20H23N5O3S2
IUPAC name	1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-N-(4-sulfamoylphenyl)piperidine-4-carboxamide
Molecular weight	445.556
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	2.7
Synonyms	HMS3047F10 879303-54-5 MolPort-005-812-732 Z79380012 1-{5,6-dimethylthieno[2,3-d]pyrimidin-4-yl}-N-(4-sulfamoylphenyl)piperidine-4-carboxamide MCULE-3003439188 AKOS034588715 SMR001240658 ZINC9463222 MLS002158182 VU0473619-1 BDBM50174737 [ Show all ]
Inchi Key	CBQRSKMWUASQDA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H23N5O3S2/c1-12-13(2)29-20-17(12)18(22-11-23-20)25-9-7-14(8-10-25)19(26)24-15-3-5-16(6-4-15)30(21,27)28/h3-6,11,14H,7-10H2,1-2H3,(H,24,26)(H2,21,27,28)
PubChem CID	16309462
ChEMBL	CHEMBL1357034
IUPHAR	N/A
BindingDB	50174737
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
522659	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
522660	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478

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