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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL320222
Molecular formula	C33H25ClF6N4O4S
IUPAC name	2-chloro-N-[2-[4-[[5-oxo-3-(4,4,4-trifluorobutyl)-1-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]phenyl]sulfonylbenzamide
Molecular weight	723.087
Hydrogen bond acceptor	11
Hydrogen bond donor	1
XlogP	7.9
Synonyms	BDBM50039858 4''-[5-Oxo-3-(4,4,4-trifluoro-butyl)-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-chloro-benzoylamide
Inchi Key	CBIPYYSLZMYMPZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H25ClF6N4O4S/c34-26-11-4-1-9-24(26)30(45)42-49(47,48)28-13-6-2-8-23(28)22-17-15-21(16-18-22)20-43-29(14-7-19-32(35,36)37)41-44(31(43)46)27-12-5-3-10-25(27)33(38,39)40/h1-6,8-13,15-18H,7,14,19-20H2,(H,42,45)
PubChem CID	10372718
ChEMBL	CHEMBL320222
IUPHAR	N/A
BindingDB	50039858
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
37917	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
37916	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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