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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL213284
Molecular formula	C31H37FN6O4
IUPAC name	(2S)-2-[(3S)-4-[(2R)-2-amino-3-(4-fluorophenyl)propanoyl]-3-[3-(carbamoylamino)propyl]-2-oxopiperazin-1-yl]-N-methyl-3-naphthalen-2-ylpropanamide
Molecular weight	576.673
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	2.3
Synonyms	BDBM50189015 1-(3-((S)-1-((R)-2-amino-3-(4-fluorophenyl)propanoyl)-4-((S)-1-(methylamino)-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-3-oxopiperazin-2-yl)propyl)urea
Inchi Key	CAPRWXCJSDCJMN-PVHODMMVSA-N
Inchi ID	InChI=1S/C31H37FN6O4/c1-35-28(39)27(19-21-8-11-22-5-2-3-6-23(22)17-21)38-16-15-37(26(30(38)41)7-4-14-36-31(34)42)29(40)25(33)18-20-9-12-24(32)13-10-20/h2-3,5-6,8-13,17,25-27H,4,7,14-16,18-19,33H2,1H3,(H,35,39)(H3,34,36,42)/t25-,26+,27+/m1/s1
PubChem CID	44416122
ChEMBL	CHEMBL213284
IUPHAR	N/A
BindingDB	50189015
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
37420	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
37421	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
37422	Melanocyte-stimulating hormone receptor	Q01726	MC1R	Homo sapiens (Human)	317

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