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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL99590
Molecular formula	C18H25N5O2
IUPAC name	3-cyclopropyl-N-[2-(4-methylpiperazin-1-yl)ethyl]-2-oxobenzimidazole-1-carboxamide
Molecular weight	343.431
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	1.5
Synonyms	3-Cyclopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid [2-(4-methyl-piperazin-1-yl)-ethyl]-amide BDBM50079285 3-Cyclopropyl-N-[2-(4-methylpiperazino)ethyl]-2-oxo-2,3-dihydro-1H-benzimidazole-1-carboxamide
Inchi Key	CAAUXNQASKNABQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H25N5O2/c1-20-10-12-21(13-11-20)9-8-19-17(24)23-16-5-3-2-4-15(16)22(18(23)25)14-6-7-14/h2-5,14H,6-13H2,1H3,(H,19,24)
PubChem CID	10688750
ChEMBL	CHEMBL99590
IUPHAR	N/A
BindingDB	50079285
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
37004	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388

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