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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL453249
Molecular formula	C17H21N5O2
IUPAC name	tert-butyl 4-(1-pyridin-3-yltriazol-4-yl)-3,6-dihydro-2H-pyridine-1-carboxylate
Molecular weight	327.388
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	1.4
Synonyms	tert-Butyl-4-[1-pyridin-3-yl-1 H-1,2,3-triazol-4-yl]-3,6-dihydropyridine-1(2H)-carboxylate BZAKDBCUMWDPGV-UHFFFAOYSA-N SCHEMBL12975527 tert-Butyl 4-[1-(pyridin-3-yl)-1H-[1,2,3]triazol-4-yl]-1,2,3,6-tetrahydropyridine-1-carboxylate BDBM50273896
Inchi Key	BZAKDBCUMWDPGV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H21N5O2/c1-17(2,3)24-16(23)21-9-6-13(7-10-21)15-12-22(20-19-15)14-5-4-8-18-11-14/h4-6,8,11-12H,7,9-10H2,1-3H3
PubChem CID	44588461
ChEMBL	CHEMBL453249
IUPHAR	N/A
BindingDB	50273896
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
36254	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
36255	Metabotropic glutamate receptor 1	P97772	Grm1	Mus musculus (Mouse)	1199
36256	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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