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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3644383
Molecular formula	C21H21N5O
IUPAC name	9-cyclopropyl-2-(4-cyclopropylimidazol-1-yl)-7,8-dihydro-4H-[1,4]diazepino[7,1-a][2,6]naphthyridin-5-one
Molecular weight	359.433
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	1.1
Synonyms	SCHEMBL15487776 US8853203, 110a BDBM136092
Inchi Key	BYWQDLWHKFJLHC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H21N5O/c27-20-10-23-19(25-11-17(24-12-25)13-1-2-13)9-18-15-5-7-22-21(14-3-4-14)16(15)6-8-26(18)20/h5,7,9,11-14H,1-4,6,8,10H2
PubChem CID	89979995
ChEMBL	CHEMBL3644383
IUPHAR	N/A
BindingDB	136092
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
459540	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
459539	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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