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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL291182
Molecular formula	C21H28F3NO4
IUPAC name	7-[(2S)-2-[(3R)-3-hydroxy-3-[3-(trifluoromethyl)phenyl]propyl]-5-oxopyrrolidin-1-yl]heptanoic acid
Molecular weight	415.453
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.4
Synonyms	BDBM50142489 SCHEMBL5735404 7-{(S)-2-[(R)-3-Hydroxy-3-(3-trifluoromethyl-phenyl)-propyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acid
Inchi Key	BUAJWRNWBMLUCH-ZWKOTPCHSA-N
Inchi ID	InChI=1S/C21H28F3NO4/c22-21(23,24)16-7-5-6-15(14-16)18(26)11-9-17-10-12-19(27)25(17)13-4-2-1-3-8-20(28)29/h5-7,14,17-18,26H,1-4,8-13H2,(H,28,29)/t17-,18+/m0/s1
PubChem CID	44289968
ChEMBL	CHEMBL291182
IUPHAR	N/A
BindingDB	50142489
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
32856	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
32855	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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