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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL144901
Molecular formula	C25H29FN4O
IUPAC name	1-[2-[4-[3-(4-fluorophenyl)-7-methylindol-1-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
Molecular weight	420.532
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.7
Synonyms	1-[2-[4-[3-(4-Fluorophenyl)-7-methyl-1H-indol-1-yl]-1-piperidinyl]ethyl]imidazolidin-2-one 1-(2-{4-[3-(4-Fluoro-phenyl)-7-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one BDBM50001814
Inchi Key	BTXNBVXZBBDLMA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H29FN4O/c1-18-3-2-4-22-23(19-5-7-20(26)8-6-19)17-30(24(18)22)21-9-12-28(13-10-21)15-16-29-14-11-27-25(29)31/h2-8,17,21H,9-16H2,1H3,(H,27,31)
PubChem CID	10047772
ChEMBL	CHEMBL144901
IUPHAR	N/A
BindingDB	50001814
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
32779	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
32780	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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