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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1760210
Molecular formula	C22H24N4O2
IUPAC name	[4-(2-methoxyphenyl)piperazin-1-yl]-[3-(4-methylphenyl)-1H-pyrazol-5-yl]methanone
Molecular weight	376.46
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.6
Synonyms	BDBM50341106 [4-(2-methoxyphenyl)piperazin-1-yl][5-(4-methylphenyl)-1H-pyrazol-3-yl]methanone MCULE-5750810211 (4-(2-methoxyphenyl)piperazin-1-yl)(3-p-tolyl-1H-pyrazol-5-yl)methanone STK901328 AKOS001828408 MolPort-007-646-273 1-(2-methoxyphenyl)-4-{[3-(4-methylphenyl)-1H-pyrazol-5-yl]carbonyl}piperazine ZINC13366568 AKOS005650090 MolPort-008-329-339 [ Show all ]
Inchi Key	BTMNKUAAPTWKSB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24N4O2/c1-16-7-9-17(10-8-16)18-15-19(24-23-18)22(27)26-13-11-25(12-14-26)20-5-3-4-6-21(20)28-2/h3-10,15H,11-14H2,1-2H3,(H,23,24)
PubChem CID	20864936
ChEMBL	CHEMBL1760210
IUPHAR	N/A
BindingDB	50341106
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
32464	Neuromedin-K receptor	P29371	TACR3	Homo sapiens (Human)	465

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