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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL104344
Molecular formula	C23H27ClN2O4S
IUPAC name	4-chloro-N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]benzenesulfonamide
Molecular weight	462.989
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.9
Synonyms	BDBM50119728 N-[(3S)-1-[3-[4-(Cyclopropylcarbonyl)phenoxy]propyl]pyrrolidine-3beta-yl]-4-chlorobenzenesulfonamide 4-Chloro-N-{(S)-1-[3-(4-cyclopropanecarbonyl-phenoxy)-propyl]-pyrrolidin-3-yl}-benzenesulfonamide
Inchi Key	BTCOIJOGNYPDOY-FQEVSTJZSA-N
Inchi ID	InChI=1S/C23H27ClN2O4S/c24-19-6-10-22(11-7-19)31(28,29)25-20-12-14-26(16-20)13-1-15-30-21-8-4-18(5-9-21)23(27)17-2-3-17/h4-11,17,20,25H,1-3,12-16H2/t20-/m0/s1
PubChem CID	44334406
ChEMBL	CHEMBL104344
IUPHAR	N/A
BindingDB	50119728
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
32218	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
32216	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
32217	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445

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