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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2160067
Molecular formula	C28H25ClN6O
IUPAC name	N-[4-chloro-3-(5-phenyl-1H-imidazol-2-yl)phenyl]-2-[(2R)-2-methylmorpholin-4-yl]-1,6-naphthyridin-5-amine
Molecular weight	496.999
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.6
Synonyms	SCHEMBL1624551 BDBM50394397 N-[3-(5-Phenyl-1H-imidazole-2-yl)-4-chlorophenyl]-2-[(2R)-2alpha-methylmorpholino]-1,6-naphthyridine-5-amine
Inchi Key	BSQHKYLMKDAHEX-GOSISDBHSA-N
Inchi ID	InChI=1S/C28H25ClN6O/c1-18-17-35(13-14-36-18)26-10-8-21-24(33-26)11-12-30-27(21)32-20-7-9-23(29)22(15-20)28-31-16-25(34-28)19-5-3-2-4-6-19/h2-12,15-16,18H,13-14,17H2,1H3,(H,30,32)(H,31,34)/t18-/m1/s1
PubChem CID	49840814
ChEMBL	CHEMBL2160067
IUPHAR	N/A
BindingDB	50394397
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
31906	Smoothened homolog	P56726	Smo	Mus musculus (Mouse)	793
31907	Smoothened homolog	Q99835	SMO	Homo sapiens (Human)	787

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