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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL197429
Molecular formula	C28H28ClFN4O
IUPAC name	3-(3-chloro-4-fluorophenyl)-1-[[4-(3-cyanophenyl)phenyl]methyl]-1-(3-pyrrolidin-1-ylpropyl)urea
Molecular weight	491.007
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.6
Synonyms	BDBM50174828 3-(3-chloro-4-fluoro-phenyl)-1-(3''-cyano-biphenyl-4-ylmethyl)-1-(3-pyrrolidin-1-yl-propyl)-urea
Inchi Key	BPFHLARZSZGTAE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H28ClFN4O/c29-26-18-25(11-12-27(26)30)32-28(35)34(16-4-15-33-13-1-2-14-33)20-21-7-9-23(10-8-21)24-6-3-5-22(17-24)19-31/h3,5-12,17-18H,1-2,4,13-16,20H2,(H,32,35)
PubChem CID	44405421
ChEMBL	CHEMBL197429
IUPHAR	N/A
BindingDB	50174828
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29499	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
29500	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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