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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL111933
Molecular formula	C29H28F3N3O3
IUPAC name	1-[(2,6-difluorophenyl)methyl]-3-[(2R)-1-[(3-fluorophenyl)methylamino]propan-2-yl]-5-(3-methoxyphenyl)-6-methylpyrimidine-2,4-dione
Molecular weight	523.556
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.7
Synonyms	1-(2,6-Difluoro-benzyl)-3-[(R)-2-(3-fluoro-benzylamino)-1-methyl-ethyl]-5-(3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione BDBM50132749 1-(2,6-Difluorobenzyl)-3-[(R)-1-methyl-2-(3-fluorobenzylamino)ethyl]-5-(3-methoxyphenyl)-6-methyluracil
Inchi Key	BNVVTOQKKGNWTP-GOSISDBHSA-N
Inchi ID	InChI=1S/C29H28F3N3O3/c1-18(15-33-16-20-7-4-9-22(30)13-20)35-28(36)27(21-8-5-10-23(14-21)38-3)19(2)34(29(35)37)17-24-25(31)11-6-12-26(24)32/h4-14,18,33H,15-17H2,1-3H3/t18-/m1/s1
PubChem CID	44340824
ChEMBL	CHEMBL111933
IUPHAR	N/A
BindingDB	50132749
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
28481	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328

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