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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-7CDW97HUEX
Molecular formula	C22H15F3N2O7S
IUPAC name	3-[5-[(2,3-difluoro-6-methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl]-2,4-dioxo-1H-thieno[3,4-d]pyrimidine-5-carboxylic acid
Molecular weight	508.424
Hydrogen bond acceptor	11
Hydrogen bond donor	2
XlogP	3.4
Synonyms	BDBM160329 Linzagolix 7CDW97HUEX SCHEMBL2333748 US9040693, 233 Linzagolix [INN] 935283-04-8 Thieno(3,4-d)pyrimidine-5-carboxylic acid, 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl)-1,2,3,4-tetrahydro-2,4-dioxo- CHEMBL3668014 3-[5-(2,3-Difluoro-6-methoxybenzyloxy)-2-fluoro-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid OBE-2109 [ Show all ]
Inchi Key	BMAAMIIYNNPHAB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H15F3N2O7S/c1-32-14-4-3-10(23)18(25)9(14)7-34-16-6-13(11(24)5-15(16)33-2)27-20(28)17-12(26-22(27)31)8-35-19(17)21(29)30/h3-6,8H,7H2,1-2H3,(H,26,31)(H,29,30)
PubChem CID	16656889
ChEMBL	CHEMBL3668014
IUPHAR	N/A
BindingDB	160329
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
459454	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328

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