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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL15729
Molecular formula	C28H28ClN3O3
IUPAC name	2-[2-chloro-4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-6-prop-2-enylphenoxy]-2-phenylacetic acid
Molecular weight	490.0
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.9
Synonyms	[2-Allyl-6-chloro-4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenoxy]-phenyl-acetic acid BDBM50284439 3-[4-(1-carboxy-1-phenylmethoxy )-3-chloro-5-(prop -2-ene-1-yl)phenylmethyl]-5,7-dimethyl-2-ethyl-3H-imidazo[4,5-b]-pyridine BLNGJVAUJVYIMH-UHFFFAOYSA-N SCHEMBL9307592
Inchi Key	BLNGJVAUJVYIMH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H28ClN3O3/c1-5-10-21-14-19(16-32-23(6-2)31-24-17(3)13-18(4)30-27(24)32)15-22(29)25(21)35-26(28(33)34)20-11-8-7-9-12-20/h5,7-9,11-15,26H,1,6,10,16H2,2-4H3,(H,33,34)
PubChem CID	18950607
ChEMBL	CHEMBL15729
IUPHAR	N/A
BindingDB	50284439
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
26816	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
26817	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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