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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Sepetaprost
Molecular formula	C26H36F2O6
IUPAC name	propan-2-yl 4-[(3S,5aR,6R,7R,8aS)-6-[(E,3R)-4-(2,5-difluorophenoxy)-3-hydroxybut-1-enyl]-7-hydroxy-3,4,5,5a,6,7,8,8a-octahydro-2H-cyclopenta[b]oxepin-3-yl]butanoate
Molecular weight	482.565
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	3.8
Synonyms	DB12043 1262873-06-2 SCHEMBL3702088 79O7855J4G UNII-79O7855J4G GTPL9875 2-Propanyl 4-((3S,5aR,6R,7R,8aS)-6-((1E,3R)-4-(2,5-difluorophenoxy)-3-hydroxy-1-buten-1-7-hydroxyoctahydro-2H-cyclopenta(b)oxepin-3-yl)butanoate propan-2-yl 4-[(3S,5aR,6R,7R,8aS)-6-[(E,3R)-4-(2,5-difluorophenoxy)-3-hydroxybut-1-enyl]-7-hydroxy-3,4,5,5a,6,7,8,8a-octahydro-2H-cyclopenta[b]oxepin-3-yl]butanoate 2H-Cyclopent(b)oxepin-3-butanoic acid, 6-((1E,3R)-4-(2,5-difluorophenoxy)-3-hydroxy-1-buten-1-yl)octahydro-7-hydroxy-, 1-methylethyl ester, (3S,5aR,6R,7R,8aS)- Sepetaprost [INN] [ Show all ]
Inchi Key	BKVUSNOUTQMSBE-XCMGCKIWSA-N
Inchi ID	InChI=1S/C26H36F2O6/c1-16(2)34-26(31)5-3-4-17-6-9-21-20(23(30)13-24(21)32-14-17)10-8-19(29)15-33-25-12-18(27)7-11-22(25)28/h7-8,10-12,16-17,19-21,23-24,29-30H,3-6,9,13-15H2,1-2H3/b10-8+/t17-,19+,20+,21+,23+,24-/m0/s1
PubChem CID	50902259
ChEMBL	N/A
IUPHAR	9875
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553390	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359

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