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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AZD-1979
Molecular formula	C25H26N4O5
IUPAC name	[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-[3-[4-(2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenoxy]azetidin-1-yl]methanone
Molecular weight	462.506
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	2.0
Synonyms	H9HGK5C4UM AZD 1979 [WHO-DD] BDBM50159343 Methanone, (5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)(3-(4-(2-oxa-6-azaspiro(3.3)hept-6-ylmethyl)phenoxy)-1-azetidinyl)- (3-(4-(2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenoxy)azetidin-1-yl)(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanone CHEMBL3787394 UNII-H9HGK5C4UM AKOS030629090 HY-U00257 CHEBI:139154 SB19727 1254035-84-1 CS-7456 [5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]{3-[4-(2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenoxy]azetidin-1-yl}methanone AZD 1979 AZD1979 J3.618.054D SCHEMBL113480 [ Show all ]
Inchi Key	BKKPIQPFRAPEAY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26N4O5/c1-31-19-8-4-18(5-9-19)22-26-27-23(34-22)24(30)29-11-21(12-29)33-20-6-2-17(3-7-20)10-28-13-25(14-28)15-32-16-25/h2-9,21H,10-16H2,1H3
PubChem CID	49801838
ChEMBL	CHEMBL3787394
IUPHAR	N/A
BindingDB	50159343
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
522350	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
522349	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
522351	Melanin-concentrating hormone receptor 1	Q8JZL2	Mchr1	Mus musculus (Mouse)	353
522348	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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