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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL474302
Molecular formula	C30H25F3N2O
IUPAC name	N-[(2S)-2-anilino-2,3-dihydro-1H-inden-5-yl]-3-methyl-2-[4-(trifluoromethyl)phenyl]benzamide
Molecular weight	486.538
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	7.7
Synonyms	SCHEMBL13591616 6-Methyl-4'-trifluoromethyl-biphenyl-2-carboxylic acid ((S)-2-phenylamino-indan-5-yl)-amide (S)-6-methyl-N-(2-(phenylamino)-2,3-dihydro-1H-inden-5-yl)-4''-(trifluoromethyl)biphenyl-2-carboxamide BDBM50277296 BJLHXLVEGNRDCK-SANMLTNESA-N
Inchi Key	BJLHXLVEGNRDCK-SANMLTNESA-N
Inchi ID	InChI=1S/C30H25F3N2O/c1-19-6-5-9-27(28(19)20-10-13-23(14-11-20)30(31,32)33)29(36)35-25-15-12-21-16-26(18-22(21)17-25)34-24-7-3-2-4-8-24/h2-15,17,26,34H,16,18H2,1H3,(H,35,36)/t26-/m0/s1
PubChem CID	44591347
ChEMBL	CHEMBL474302
IUPHAR	N/A
BindingDB	50277296
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
25253	Smoothened homolog	Q99835	SMO	Homo sapiens (Human)	787
25254	Smoothened homolog	P56726	Smo	Mus musculus (Mouse)	793

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