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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL290768
Molecular formula	C37H31N7O2S
IUPAC name	N-benzyl-N-[4-oxo-2-propan-2-yl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]quinazolin-6-yl]thiophene-2-carboxamide
Molecular weight	637.762
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	6.8
Synonyms	Thiophene-2-carboxylic acid benzyl-{2-isopropyl-4-oxo-3-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,4-dihydro-quinazolin-6-yl}-amide BDBM50282702
Inchi Key	BJEGHUOJTHEZOS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C37H31N7O2S/c1-24(2)35-38-32-19-18-28(43(22-25-9-4-3-5-10-25)37(46)33-13-8-20-47-33)21-31(32)36(45)44(35)23-26-14-16-27(17-15-26)29-11-6-7-12-30(29)34-39-41-42-40-34/h3-21,24H,22-23H2,1-2H3,(H,39,40,41,42)
PubChem CID	44283480
ChEMBL	CHEMBL290768
IUPHAR	N/A
BindingDB	50282702
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
24994	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
24993	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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