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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SB 223412
Molecular formula	C25H22N2O2
IUPAC name	3-hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
Molecular weight	382.463
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.7
Synonyms	3-hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide BCP21046 LS-185659 4-Quinolinecaeboxamide, 3-hydroxy-2-phenyl-N-((1S)-1-phenylpropyl)- CHEMBL275544 AC1L325X KB-80494 3-Hydroxy-2-phenyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide BDBM50074819 PDSP1_001725 4-Quinolinecarboxamide, 3-hydroxy-2-phenyl-N-(1-phenylpropyl)-, (S)- SCHEMBL74221 AKOS027322596 L001526 3-Hydroxy-2-phenyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide (skb_a) PDSP2_001708 J-690242 [ Show all ]
Inchi Key	BIAVGWDGIJKWRM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H22N2O2/c1-2-20(17-11-5-3-6-12-17)27-25(29)22-19-15-9-10-16-21(19)26-23(24(22)28)18-13-7-4-8-14-18/h3-16,20,28H,2H2,1H3,(H,27,29)
PubChem CID	133090
ChEMBL	CHEMBL275544
IUPHAR	N/A
BindingDB	50074819
DrugBank	DB06429
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
24276	Neuromedin-K receptor	P29371	TACR3	Homo sapiens (Human)	465
24277	Substance-K receptor	P21452	TACR2	Homo sapiens (Human)	398
24278	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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