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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4-[(2E)-2-(2,4-dimethoxybenzylidene)hydrazinyl]-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidine
Molecular formula	C19H22N6O2
IUPAC name	N-[(E)-(2,4-dimethoxyphenyl)methylideneamino]-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
Molecular weight	366.425
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.6
Synonyms	AKOS005377863 MolPort-002-539-013 302798-94-3 STK016836 CHEMBL3191846
Inchi Key	BHIUFNZKXFDGDQ-RGVLZGJSSA-N
Inchi ID	InChI=1S/C19H22N6O2/c1-12-9-18(22-19(21-12)25-14(3)8-13(2)24-25)23-20-11-15-6-7-16(26-4)10-17(15)27-5/h6-11H,1-5H3,(H,21,22,23)/b20-11+
PubChem CID	9608279
ChEMBL	CHEMBL3191846
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23791	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
23792	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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