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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL180372
Molecular formula	C25H21ClF2N4O4
IUPAC name	1-[(2R)-2-amino-2-phenylethyl]-3-[(2-chloro-6-fluorophenyl)methyl]-5-(2-fluoro-3-methoxyphenyl)-1,3,5-triazinane-2,4,6-trione
Molecular weight	514.914
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.8
Synonyms	BDBM50168722 1-((R)-2-Amino-2-phenyl-ethyl)-3-(2-chloro-6-fluoro-benzyl)-5-(2-fluoro-3-methoxy-phenyl)-[1,3,5]triazinane-2,4,6-trione
Inchi Key	BEMWHSSLIDMZQS-IBGZPJMESA-N
Inchi ID	InChI=1S/C25H21ClF2N4O4/c1-36-21-12-6-11-20(22(21)28)32-24(34)30(13-16-17(26)9-5-10-18(16)27)23(33)31(25(32)35)14-19(29)15-7-3-2-4-8-15/h2-12,19H,13-14,29H2,1H3/t19-/m0/s1
PubChem CID	44387972
ChEMBL	CHEMBL180372
IUPHAR	N/A
BindingDB	50168722
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21723	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328

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