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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL474892
Molecular formula	C28H24F3N3OS
IUPAC name	3-methyl-N-[(2R)-2-(1,3-thiazol-2-ylmethylamino)-2,3-dihydro-1H-inden-5-yl]-2-[4-(trifluoromethyl)phenyl]benzamide
Molecular weight	507.575
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	6.1
Synonyms	(R)-6-methyl-N-(2-(thiazol-2-ylmethylamino)-2,3-dihydro-1H-inden-5-yl)-4''-(trifluoromethyl)biphenyl-2-carboxamide BDBM50277189
Inchi Key	BDOBNHGYFGVFDD-HSZRJFAPSA-N
Inchi ID	InChI=1S/C28H24F3N3OS/c1-17-3-2-4-24(26(17)18-5-8-21(9-6-18)28(29,30)31)27(35)34-22-10-7-19-13-23(15-20(19)14-22)33-16-25-32-11-12-36-25/h2-12,14,23,33H,13,15-16H2,1H3,(H,34,35)/t23-/m1/s1
PubChem CID	25211677
ChEMBL	CHEMBL474892
IUPHAR	N/A
BindingDB	50277189
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21111	Smoothened homolog	P56726	Smo	Mus musculus (Mouse)	793
21112	Smoothened homolog	Q99835	SMO	Homo sapiens (Human)	787

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