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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1084383
Molecular formula	C21H23N5S
IUPAC name	6-methyl-5-[6-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]quinolin-2-yl]-[1,3]thiazolo[3,2-b][1,2,4]triazole
Molecular weight	377.51
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.4
Synonyms	BDBM50319552 SCHEMBL3456167 (R)-6-methyl-5-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinolin-2-yl)thiazolo[3,2-b][1,2,4]triazole
Inchi Key	BCSPALWWQLYRIR-CQSZACIVSA-N
Inchi ID	InChI=1S/C21H23N5S/c1-14-4-3-10-25(14)11-9-16-5-7-18-17(12-16)6-8-19(24-18)20-15(2)26-21(27-20)22-13-23-26/h5-8,12-14H,3-4,9-11H2,1-2H3/t14-/m1/s1
PubChem CID	11516392
ChEMBL	CHEMBL1084383
IUPHAR	N/A
BindingDB	50319552
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20479	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
20480	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445

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