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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2163722
Molecular formula	C25H25BrN8O7S
IUPAC name	N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]morpholine-4-sulfonamide
Molecular weight	661.488
Hydrogen bond acceptor	15
Hydrogen bond donor	1
XlogP	1.8
Synonyms	BDBM50395644
Inchi Key	BCPQODVHPDJJAT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H25BrN8O7S/c1-37-18-5-2-3-6-19(18)41-20-21(33-42(35,36)34-9-11-38-12-10-34)31-23(22-27-7-4-8-28-22)32-24(20)39-13-14-40-25-29-15-17(26)16-30-25/h2-8,15-16H,9-14H2,1H3,(H,31,32,33)
PubChem CID	71460537
ChEMBL	CHEMBL2163722
IUPHAR	N/A
BindingDB	50395644
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20387	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
20388	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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