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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL195522
Molecular formula	C17H14ClN3O2
IUPAC name	N-[(4-chlorophenyl)methyl]-7-methyl-4-oxo-1H-1,8-naphthyridine-3-carboxamide
Molecular weight	327.768
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.4
Synonyms	BCPIVBRTJNYLEK-UHFFFAOYSA-N SCHEMBL6695156 BDBM50171783 N-(4-chlorobenzyl)-4-hydroxy-7-methyl[1,8]naphthyridine-3-carboxamide 7-Methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid 4-chloro-benzylamide 1,8-Naphthyridine-3-carboxamide, N-[(4-chlorophenyl)methyl]-4-hydroxy-7-methyl- N-[(4-chlorophenyl)methyl]-4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxamide [ Show all ]
Inchi Key	BCPIVBRTJNYLEK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H14ClN3O2/c1-10-2-7-13-15(22)14(9-19-16(13)21-10)17(23)20-8-11-3-5-12(18)6-4-11/h2-7,9H,8H2,1H3,(H,20,23)(H,19,21,22)
PubChem CID	9945283
ChEMBL	CHEMBL195522
IUPHAR	N/A
BindingDB	50171783
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20384	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
20385	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
20383	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412

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