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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL490692
Molecular formula	C28H21ClN2O4S
IUPAC name	(E)-N-(3-chlorophenyl)sulfonyl-3-(1-methyl-4-naphthalen-2-yloxyindol-3-yl)prop-2-enamide
Molecular weight	516.996
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.2
Synonyms	BDBM50247940 N-(3-chlorophenylsulfonyl)-3-(1-methyl-4-(naphthalen-2-yloxy)-1H-indol-3-yl)acrylamide
Inchi Key	BBLJIUZOXCSNOX-FYWRMAATSA-N
Inchi ID	InChI=1S/C28H21ClN2O4S/c1-31-18-21(13-15-27(32)30-36(33,34)24-9-4-8-22(29)17-24)28-25(31)10-5-11-26(28)35-23-14-12-19-6-2-3-7-20(19)16-23/h2-18H,1H3,(H,30,32)/b15-13+
PubChem CID	44564572
ChEMBL	CHEMBL490692
IUPHAR	N/A
BindingDB	50247940
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
19596	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390

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