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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000074933
Molecular formula	C18H17ClN4O
IUPAC name	5-(4-chlorophenyl)-7-(2-methoxyphenyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine
Molecular weight	340.811
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.2
Synonyms	MolPort-002-124-220 AKOS002132294 CHEMBL1463698 SR-01000586711 MCULE-6691158934 Oprea1_013652 BDBM62072 cid_5738863 SR-01000586711-1 5-(4-chlorophenyl)-7-(2-methoxyphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine MLS000049199 AC1NWY8X HMS2273P19 ZINC00222187 5-(4-chlorophenyl)-7-(2-methoxyphenyl)-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidine [ Show all ]
Inchi Key	BAIZGCLOUWAISR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H17ClN4O/c1-24-17-5-3-2-4-14(17)16-10-15(12-6-8-13(19)9-7-12)22-18-20-11-21-23(16)18/h2-9,11,15-16H,10H2,1H3,(H,20,21,22)
PubChem CID	2948210
ChEMBL	CHEMBL1463698
IUPHAR	N/A
BindingDB	62072
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18915	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
18912	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
18914	Neuropeptides B/W receptor type 1	P48145	NPBWR1	Homo sapiens (Human)	328
18913	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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