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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL410435
Molecular formula	C33H29N3O2
IUPAC name	1-benzyl-3-[(1-benzylindol-3-yl)methyl]-9-methyl-3,4-dihydro-1,4-benzodiazepine-2,5-dione
Molecular weight	499.614
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.9
Synonyms	BDBM50374119
Inchi Key	AZKFUYPRWRRXSX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H29N3O2/c1-23-11-10-17-28-31(23)36(21-25-14-6-3-7-15-25)33(38)29(34-32(28)37)19-26-22-35(20-24-12-4-2-5-13-24)30-18-9-8-16-27(26)30/h2-18,22,29H,19-21H2,1H3,(H,34,37)
PubChem CID	44457022
ChEMBL	CHEMBL410435
IUPHAR	N/A
BindingDB	50374119
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18261	Melanocortin receptor 3	P33033	Mc3r	Mus musculus (Mouse)	323
18262	Melanocortin receptor 4	P56450	Mc4r	Mus musculus (Mouse)	332
18260	Melanocortin receptor 5	P41149	Mc5r	Mus musculus (Mouse)	325
18259	Melanocyte-stimulating hormone receptor	Q01727	Mc1r	Mus musculus (Mouse)	315

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