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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL322283
Molecular formula	C22H23F2N3O3
IUPAC name	3-[(2S)-2-aminopropyl]-1-[(2,6-difluorophenyl)methyl]-5-(3-methoxyphenyl)-6-methylpyrimidine-2,4-dione
Molecular weight	415.441
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.6
Synonyms	BDBM50132741 3-((S)-2-Amino-propyl)-1-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione 1-(2,6-Difluorobenzyl)-3-[(S)-2-aminopropyl]-5-(3-methoxyphenyl)-6-methyluracil
Inchi Key	AYPFBVKPMHZLON-ZDUSSCGKSA-N
Inchi ID	InChI=1S/C22H23F2N3O3/c1-13(25)11-27-21(28)20(15-6-4-7-16(10-15)30-3)14(2)26(22(27)29)12-17-18(23)8-5-9-19(17)24/h4-10,13H,11-12,25H2,1-3H3/t13-/m0/s1
PubChem CID	44340649
ChEMBL	CHEMBL322283
IUPHAR	N/A
BindingDB	50132741
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17657	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328

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