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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000016951
Molecular formula	C21H19N3O5
IUPAC name	N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3,4-dimethylphenyl)-2,4-dioxo-1H-pyrimidine-5-carboxamide
Molecular weight	393.399
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.3
Synonyms	AKOS001893988 MLS000102810 ZINC2916908 cid_3242073 N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3,4-dimethylphenyl)-2,4-diketo-1H-pyrimidine-5-carboxamide MCULE-3871135898 N-2,3-dihydro-1,4-benzodioxin-6-yl-3-(3,4-dimethylphenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide BDBM37332 MolPort-003-050-996 F0696-0370 N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3,4-dimethylphenyl)-2,4-dioxo-1H-pyrimidine-5-carboxamide AC1MMORW MLS000094454 CHEMBL1456172 N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3,4-dimethylphenyl)-2,4-bis(oxidanylidene)-1H-pyrimidine-5-carboxamide HMS2493O16 N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-(3,4-dimethylphenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide [ Show all ]
Inchi Key	AYDRQXWCJIQSOB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H19N3O5/c1-12-3-5-15(9-13(12)2)24-20(26)16(11-22-21(24)27)19(25)23-14-4-6-17-18(10-14)29-8-7-28-17/h3-6,9-11H,7-8H2,1-2H3,(H,22,27)(H,23,25)
PubChem CID	3242073
ChEMBL	N/A
IUPHAR	N/A
BindingDB	37332
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17366	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378

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