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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	(5Z)-5-(4-hydroxybenzylidene)-3-(tetrahydrofuran-2-ylmethyl)-2-thioxo-1,3-thiazolidin-4-one
Molecular formula	C15H15NO3S2
IUPAC name	(5Z)-5-[(4-hydroxyphenyl)methylidene]-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one
Molecular weight	321.409
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.0
Synonyms	HMS2772P03 5-[1-(4-Hydroxy-phenyl)-meth-(Z)-ylidene]-3-(tetrahydro-furan-2-ylmethyl)-2-thioxo-thiazolidin-4-one AKOS016289424 MolPort-000-419-860 CHEMBL1441706 SR-01000082508-1 (Z)-5-(4-hydroxybenzylidene)-3-((tetrahydrofuran-2-yl)methyl)-2-thioxothiazolidin-4-one IDI1_021352 AC1NZC1K BRD-A02131828-001-01-6 SMR000414792 HMS1482M10 STK877464 438460-08-3 MLS000807050 AKOS000350827 SR-01000082508 (5Z)-5-[(4-hydroxyphenyl)methylidene]-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one [ Show all ]
Inchi Key	AWFVCJJDTXVPDE-JYRVWZFOSA-N
Inchi ID	InChI=1S/C15H15NO3S2/c17-11-5-3-10(4-6-11)8-13-14(18)16(15(20)21-13)9-12-2-1-7-19-12/h3-6,8,12,17H,1-2,7,9H2/b13-8-
PubChem CID	5929780
ChEMBL	CHEMBL1441706
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15983	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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