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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL603049
Molecular formula	C21H23FN2
IUPAC name	8-fluoro-2-methyl-5-[2-(4-methylphenyl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole
Molecular weight	322.427
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	4.3
Synonyms	8-Fluoro-2-methyl-5-(2-p-tolylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole ZINC45387342 BDBM50305268 MolPort-021-806-385 8-fluoro-2-methyl-5-(4-methylphenethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole SCHEMBL1224355 AKOS021644596 [ Show all ]
Inchi Key	AVZFSLTZULXZCC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H23FN2/c1-15-3-5-16(6-4-15)9-12-24-20-8-7-17(22)13-18(20)19-14-23(2)11-10-21(19)24/h3-8,13H,9-12,14H2,1-2H3
PubChem CID	44126328
ChEMBL	CHEMBL603049
IUPHAR	N/A
BindingDB	50305268
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15780	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
15779	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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