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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL63426
Molecular formula	C23H25N5
IUPAC name	3-N-cyclopropyl-7-[(4-propan-2-ylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine
Molecular weight	371.488
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.9
Synonyms	SCHEMBL1760395 AC1N6FKN n3-cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7h-pyrrolo[3,2-f]quinazoline-1,3-diamine SCH-79797 BRD-K17140735-300-01-6 Tocris-1592 3-N-cyclopropyl-7-[(4-propan-2-ylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine BCP21206 NCGC00025225-01 Sch79797/Sch-79797 CHEBI:94998 ZINC1490299 N3-Cyclopropyl-7-(4-isopropyl-benzyl)-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine BDBM50079751 NCGC00025225-02 [ Show all ]
Inchi Key	AVXQPEKZIGPIJW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25N5/c1-14(2)16-5-3-15(4-6-16)13-28-12-11-18-20(28)10-9-19-21(18)22(24)27-23(26-19)25-17-7-8-17/h3-6,9-12,14,17H,7-8,13H2,1-2H3,(H3,24,25,26,27)
PubChem CID	4259181
ChEMBL	CHEMBL63426
IUPHAR	N/A
BindingDB	50079751
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15750	Proteinase-activated receptor 1	P25116	F2R	Homo sapiens (Human)	425
15751	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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