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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL215654
Molecular formula	C29H30F6N2O
IUPAC name	N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-cyclopropyl-4-spiro[indene-1,4'-piperidine]-1'-ylbutanamide
Molecular weight	536.562
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	7.1
Synonyms	BDBM50191798 N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-cyclopropyl-4-{spiro[indene-1,4''-piperidine]-1''-yl}butanamide
Inchi Key	AUGHKPPZWXWECG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H30F6N2O/c30-28(31,32)22-15-19(16-23(17-22)29(33,34)35)18-36-26(38)24(20-5-6-20)8-12-37-13-10-27(11-14-37)9-7-21-3-1-2-4-25(21)27/h1-4,7,9,15-17,20,24H,5-6,8,10-14,18H2,(H,36,38)
PubChem CID	44415898
ChEMBL	CHEMBL215654
IUPHAR	N/A
BindingDB	50191798
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
14613	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374

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