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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	TCMDC-139117
Molecular formula	C25H30Cl2N4O
IUPAC name	1-(3,4-dichlorophenyl)-3-[5-[4-(1H-indol-3-yl)piperidin-1-yl]pentyl]urea
Molecular weight	473.442
Hydrogen bond acceptor	2
Hydrogen bond donor	3
XlogP	5.7
Synonyms	CHEMBL300025 1-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-3-(3,4-dichlorophenyl)urea BDBM50091441 3-[1-[5-[3-(3,4-Dichlorophenyl)ureido]pentyl]-4-piperidinyl]-1H-indole 1-(3,4-Dichloro-phenyl)-3-{5-[4-(1H-indol-3-yl)-piperidin-1-yl]-pentyl}-urea
Inchi Key	ARMKFSFVQYRQSN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30Cl2N4O/c26-22-9-8-19(16-23(22)27)30-25(32)28-12-4-1-5-13-31-14-10-18(11-15-31)21-17-29-24-7-3-2-6-20(21)24/h2-3,6-9,16-18,29H,1,4-5,10-15H2,(H2,28,30,32)
PubChem CID	44296501
ChEMBL	CHEMBL300025
IUPHAR	N/A
BindingDB	50091441
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12579	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374

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