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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL294345
Molecular formula	C21H23NO3
IUPAC name	(11Z)-11-[4-(dimethylamino)butylidene]-6H-benzo[c][1]benzoxepine-2-carboxylic acid
Molecular weight	337.419
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	1.9
Synonyms	11-(4-Dimethylamino-butylidene)-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid BDBM50002097 SCHEMBL5060826 6,11-Dihydro-11-[(Z)-4-dimethylaminobutylidene]dibenz[b,e]oxepin-2-carboxylic acid
Inchi Key	ARFFJDYERFVHNC-NVMNQCDNSA-N
Inchi ID	InChI=1S/C21H23NO3/c1-22(2)12-6-5-9-18-17-8-4-3-7-16(17)14-25-20-11-10-15(21(23)24)13-19(18)20/h3-4,7-11,13H,5-6,12,14H2,1-2H3,(H,23,24)/b18-9-
PubChem CID	15749431
ChEMBL	CHEMBL294345
IUPHAR	N/A
BindingDB	50002097
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12409	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
12410	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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