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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL159281
Molecular formula	C23H25N3O
IUPAC name	4-[2-[2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]benzonitrile
Molecular weight	359.473
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.2
Synonyms	4-{2-[2-((S)-3-Dimethylamino-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-benzonitrile BDBM50139401 SCHEMBL2785198 4-(2-{2-[(3S)-3-(dimethylamino)pyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile ARDRZCADVURIHZ-NRFANRHFSA-N
Inchi Key	ARDRZCADVURIHZ-NRFANRHFSA-N
Inchi ID	InChI=1S/C23H25N3O/c1-25(2)21-9-11-26(16-21)12-10-22-14-20-13-19(7-8-23(20)27-22)18-5-3-17(15-24)4-6-18/h3-8,13-14,21H,9-12,16H2,1-2H3/t21-/m0/s1
PubChem CID	10067030
ChEMBL	CHEMBL159281
IUPHAR	N/A
BindingDB	50139401
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12353	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
12354	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445

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