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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL473106
Molecular formula	C17H18N2O2S2
IUPAC name	3-ethyl-4-[1-(furan-2-ylmethyl)-2,6-dimethylpyridin-4-ylidene]-2-sulfanylidene-1,3-thiazolidin-5-one
Molecular weight	346.463
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.4
Synonyms	AKOS034457995 MLS000055414 3-ethyl-4-[1-(furan-2-ylmethyl)-2,6-dimethylpyridin-4-ylidene]-2-sulfanylidene-1,3-thiazolidin-5-one SMR000066106 HMS2174A07 BDBM50247213 MolPort-004-000-989 3-ethyl-4-{1-[(furan-2-yl)methyl]-2,6-dimethyl-1,4-dihydropyridin-4-ylidene}-2-sulfanylidene-1,3-thiazolidin-5-one cid_2369069 Z56821874 AC1M69RW MCULE-5239245735 3-ethyl-4-(1-(furan-2-ylmethyl)-2,6-dimethylpyridin-4(1H)-ylidene)-2-thioxothiazolidin-5-one Oprea1_031057 380344-90-1 HMS1761B01 ZINC3252138 [ Show all ]
Inchi Key	AQWLITYTSYRLNQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18N2O2S2/c1-4-18-15(16(20)23-17(18)22)13-8-11(2)19(12(3)9-13)10-14-6-5-7-21-14/h5-9H,4,10H2,1-3H3
PubChem CID	2369069
ChEMBL	CHEMBL473106
IUPHAR	N/A
BindingDB	50247213
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12153	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
12150	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
12152	Oxytocin receptor	P30559	OXTR	Homo sapiens (Human)	389
12151	Vasopressin V1a receptor	P37288	AVPR1A	Homo sapiens (Human)	418

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