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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL521388
Molecular formula	C25H26ClF3N4O2
IUPAC name	6-chloro-3-[1-[1-[2-(trifluoromethyl)benzoyl]piperidin-4-yl]piperidin-4-yl]-1H-benzimidazol-2-one
Molecular weight	506.954
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.6
Synonyms	BDBM50275342 5-chloro-1-(1''-(2-(trifluoromethyl)benzoyl)-1,4''-bipiperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
Inchi Key	AQIOZTSTCKLBDS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26ClF3N4O2/c26-16-5-6-22-21(15-16)30-24(35)33(22)18-9-11-31(12-10-18)17-7-13-32(14-8-17)23(34)19-3-1-2-4-20(19)25(27,28)29/h1-6,15,17-18H,7-14H2,(H,30,35)
PubChem CID	44589500
ChEMBL	CHEMBL521388
IUPHAR	N/A
BindingDB	50275342
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11780	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
11781	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460

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