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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL15517
Molecular formula	C26H26ClN3O3
IUPAC name	2-[2-chloro-4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]phenoxy]-2-(2-methylphenyl)acetic acid
Molecular weight	463.962
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.1
Synonyms	SCHEMBL9127009 [2-Chloro-4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenoxy]-o-tolyl-acetic acid BDBM50284453 L005510
Inchi Key	APSWMQVSEDQAFN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H26ClN3O3/c1-5-22-29-23-16(3)12-17(4)28-25(23)30(22)14-18-10-11-21(20(27)13-18)33-24(26(31)32)19-9-7-6-8-15(19)2/h6-13,24H,5,14H2,1-4H3,(H,31,32)
PubChem CID	15229605
ChEMBL	CHEMBL15517
IUPHAR	N/A
BindingDB	50284453
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11331	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
11332	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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