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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL145712
Molecular formula	C28H35FN4O
IUPAC name	1-[2-[4-[3-(4-fluorophenyl)-5-methylindol-1-yl]piperidin-1-yl]ethyl]-3-propan-2-ylimidazolidin-2-one
Molecular weight	462.613
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.7
Synonyms	2-imidazolidinone,1-[2-[4-[3-(4-fluorophenyl)-5-methyl-1h-indol-1-yl]-1-piperidinyl]ethyl]-3-(1-methylethyl)- L006428 AOVJKFZMDSJQDY-UHFFFAOYSA-N 1-[2-[4-[3-(4-Fluorophenyl)-5-methyl-1H-indol-1-yl]-1-piperidinyl]ethyl]-3-isopropylimidazolidin-2-one 3-(4-Fluorophenyl)-5-methyl-1-[1-[2-[3-(2-propyl)imidazolidin-2-on-1yl]ethyl]-4-piperidyl)-1H-indole SCHEMBL9269223 BDBM50001808 141306-36-7 KB-284890 ZINC604452 1-(2-{4-[3-(4-Fluoro-phenyl)-5-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one [ Show all ]
Inchi Key	AOVJKFZMDSJQDY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H35FN4O/c1-20(2)32-17-16-31(28(32)34)15-14-30-12-10-24(11-13-30)33-19-26(22-5-7-23(29)8-6-22)25-18-21(3)4-9-27(25)33/h4-9,18-20,24H,10-17H2,1-3H3
PubChem CID	9956013
ChEMBL	CHEMBL145712
IUPHAR	N/A
BindingDB	50001808
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10625	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
10626	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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