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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1277492
Molecular formula	C24H24ClNO4
IUPAC name	(3R)-1-(3-chloro-5-oxospiro[benzo[b][1]benzoxepine-6,3'-cyclopentane]-1'-yl)piperidine-3-carboxylic acid
Molecular weight	425.909
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.1
Synonyms	BDBM50417377
Inchi Key	AOSLQNBDHSOLAE-HAQQTFLXSA-N
Inchi ID	InChI=1S/C24H24ClNO4/c25-16-7-8-20-18(12-16)22(27)24(19-5-1-2-6-21(19)30-20)10-9-17(13-24)26-11-3-4-15(14-26)23(28)29/h1-2,5-8,12,15,17H,3-4,9-11,13-14H2,(H,28,29)/t15-,17?,24?/m1/s1
PubChem CID	49836842
ChEMBL	CHEMBL1277492
IUPHAR	N/A
BindingDB	50417377
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10565	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
10563	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
10564	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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