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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	195055-03-9
Molecular formula	C22H32N6
IUPAC name	3-[6-(dimethylamino)-4-methylpyridin-3-yl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine
Molecular weight	380.54
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.7
Synonyms	KB-79289 R-121919 3-[6-(dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-n,n-dipropyl-pyrazolo[2,3-a]pyrimidine-7-amine ANNRUWYFVIGKHA-UHFFFAOYSA-N CHEMBL309138 NBI 30775 TC-148159 3-[6-(dimethylamino)-4-methylpyridin-3-yl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine AX8150177 DTXSID00173162 GTPL3520 R 121919 [3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dimethyl-4H-pyrazolo[1,5-a]pyrimidin-7-yl]-dipropyl-amine 3-(6-(Dimethylamino);-4-methylpyridin-3-yl);-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine AB21702 CD-1823 KS-000006AG R121919 3-[6-(dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-N,N-dipropylpyrazolo[2,3-a]-pyrimidin-7-amine ANW-59414 CS-6231 FT-0767007 NBI-30775 UNII-G82N555U1N 292073-75-7 BCP23964 HY-14127 R-121,919 [3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidin-7-yl]-dipropyl-amine 3-(6-dimethylamino-4-methylpyridin-3-yl)-2,5-dimethyl-N,N-dipropylpyrazolo[5,1-b]pyrimidin-7-amine AKOS016002213 MolPort-009-200-030 SCHEMBL5600844 0092AB 3-[6-(dimethylamino)-4-methyl-pyrid-3-yl]-2,5-dimethyl-n,n-dipropyl-pyrazolo[2,3-a]pyrimidin-7-amine API0009338 CTK8B8151 G82N555U1N Pyrazolo(1,5-a)pyrimidin-7-amine, 3-(6-(dimethylamino)-4-methyl-3-pyridinyl)-2,5-dimethyl-n,N-dipropyl- ZINC602283 3-(6-(Dimethylamino)-4-methylpyridin-3-yl)-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine BDBM50116105 [ Show all ]
Inchi Key	ANNRUWYFVIGKHA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H32N6/c1-8-10-27(11-9-2)20-13-16(4)24-22-21(17(5)25-28(20)22)18-14-23-19(26(6)7)12-15(18)3/h12-14H,8-11H2,1-7H3
PubChem CID	9821250
ChEMBL	CHEMBL309138
IUPHAR	3520
BindingDB	50116105
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9713	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444
9714	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415
464062	Corticotropin-releasing factor receptor 2	Q13324	CRHR2	Homo sapiens (Human)	411

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