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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000545777
Molecular formula	C19H19N3OS
IUPAC name	(5Z)-3-benzyl-5-[[4-(dimethylamino)phenyl]methylidene]-2-sulfanylideneimidazolidin-4-one
Molecular weight	337.441
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.5
Synonyms	(5Z)-5-[[4-(dimethylamino)phenyl]methylidene]-3-(phenylmethyl)-2-sulfanylidene-4-imidazolidinone CHEMBL1303807 (5Z)-3-benzyl-5-[4-(dimethylamino)benzylidene]-2-thioxo-4-imidazolidinone BDBM61608 (5Z)-5-[[4-(dimethylamino)phenyl]methylidene]-3-(phenylmethyl)-2-sulfanylidene-imidazolidin-4-one cid_1803281 AC1LXNB2 SMR000161071 (5Z)-3-benzyl-5-[[4-(dimethylamino)phenyl]methylidene]-2-sulfanylideneimidazolidin-4-one 3-benzyl-5-[4-(dimethylamino)benzylidene]-2-thioxo-4-imidazolidinone HMS2187J14 (5Z)-3-benzyl-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylideneimidazolidin-4-one AN-940/40648818 ZINC367358 [ Show all ]
Inchi Key	ANCIYSVAHZBPLI-ATVHPVEESA-N
Inchi ID	InChI=1S/C19H19N3OS/c1-21(2)16-10-8-14(9-11-16)12-17-18(23)22(19(24)20-17)13-15-6-4-3-5-7-15/h3-12H,13H2,1-2H3,(H,20,24)/b17-12-
PubChem CID	1803281
ChEMBL	CHEMBL1303807
IUPHAR	N/A
BindingDB	61608
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9442	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
9441	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
9443	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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