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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000703412
Molecular formula	C11H12N2O3S3
IUPAC name	2-[(5Z)-5-[(2Z)-2-(3-methyl-1,3-thiazolidin-2-ylidene)ethylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid
Molecular weight	316.408
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.0
Synonyms	2-[(5Z)-5-[(2Z)-2-(3-methylthiazolidin-2-ylidene)ethylidene]-4-oxo-2-thioxo-thiazolidin-3-yl]acetic acid 65152-09-2 CHEMBL1313434 SR-01000313604 3-Thiazolidineacetic acid, 5-((3-methyl-2-thiazolidinylidene)ethylidene)-4-oxo-2-thioxo- AN-38681 HMS2646C10 STK396547 2-[(5Z)-5-[(2Z)-2-(3-methyl-1,3-thiazolidin-2-ylidene)ethylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid 5-(2-(3-Methyl-2-thiazolidinylidene)ethylidene)-3-(carboxymethyl)-2-thioxo-4-thiazolidinone CHEBI:107451 NCGC00245171-01 2-{5-[2-(3-methyl(1,3-thiazolidin-2-ylidene))ethylidene]-4-oxo-2-thioxo-1,3-th iazolidin-3-yl}acetic acid AC1LWNJZ cid_1734123 SR-01000313604-1 2-[(5Z)-4-keto-5-[(2Z)-2-(3-methylthiazolidin-2-ylidene)ethylidene]-2-thioxo-thiazolidin-3-yl]acetic acid 3-Thiazolidineacetic acid, 5-(2-(3-methyl-2-thiazolidinylidene)ethylidene)-4-oxo-2-thioxo- BAS 00670021 ZINC13118224 2-[(5Z)-5-[(2Z)-2-(3-methyl-2-thiazolidinylidene)ethylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]acetic acid 5-[2-(3-Methylthiazolidin-2-ylidene)ethylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid SMR000273876 3-Carboxymethyl-5-((3-methyl-2-thiazolidinylidene)-ethylidene)rhodanine AKOS000732782 EINECS 265-567-0 ST50237415 2-[(5Z)-5-[(2Z)-2-(3-methyl-1,3-thiazolidin-2-ylidene)ethylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanoic acid 5-((3-Methylthiazolidin-2-ylidene)ethylidene)-4-oxo-2-thioxothiazolidin-3-acetic acid BDBM43135 MolPort-001-942-492 {(5Z)-5-[(2Z)-2-(3-methyl-1,3-thiazolidin-2-ylidene)ethylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}acetic acid [ Show all ]
Inchi Key	AMSAICQWZZDCEM-ZXCOBTLNSA-N
Inchi ID	InChI=1S/C11H12N2O3S3/c1-12-4-5-18-8(12)3-2-7-10(16)13(6-9(14)15)11(17)19-7/h2-3H,4-6H2,1H3,(H,14,15)/b7-2-,8-3-
PubChem CID	1734123
ChEMBL	CHEMBL1313434
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9190	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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