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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL116074
Molecular formula	C30H30F3N3O3
IUPAC name	1-[(2,6-difluorophenyl)methyl]-3-[(2S)-2-(dimethylamino)-3-phenylpropyl]-5-(2-fluoro-3-methoxyphenyl)-6-methylpyrimidine-2,4-dione
Molecular weight	537.583
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	5.2
Synonyms	BDBM50149256 1-(2,6-Difluoro-benzyl)-3-((S)-2-dimethylamino-3-phenyl-propyl)-5-(2-fluoro-3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione
Inchi Key	AMCFOVGLNPCZBV-NRFANRHFSA-N
Inchi ID	InChI=1S/C30H30F3N3O3/c1-19-27(22-12-8-15-26(39-4)28(22)33)29(37)36(17-21(34(2)3)16-20-10-6-5-7-11-20)30(38)35(19)18-23-24(31)13-9-14-25(23)32/h5-15,21H,16-18H2,1-4H3/t21-/m0/s1
PubChem CID	11387100
ChEMBL	CHEMBL116074
IUPHAR	N/A
BindingDB	50149256
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8740	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328

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