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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	42160-26-9
Molecular formula	C12H10N2S
IUPAC name	2-amino-4-methyl-5-phenylthiophene-3-carbonitrile
Molecular weight	214.286
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.6
Synonyms	3-Thiophenecarbonitrile, 2-amino-4-methyl-5-phenyl- BRD-K17497947-001-01-8 IDI1_012599 SR-01000635343-1 MolPort-001-920-737 2-Amino-4-methyl-5-phenyl-thiophene-3-carbonitrile BAS 00281176 DTXSID20194990 NSC209020 Cambridge id 5175071 Maybridge3_001212 UNII-4IIO6GJS6V 2-Amino-3-cyano-4-methyl-5-phenylthiophene AC1L7CIW CHEMBL565502 NSC 209020 2-Amino-4-methyl-5-phenylthiophene-3-carbonitrile BDBM50299479 HMS1434H02 SCHEMBL10710844 4IIO6GJS6V CCG-45588 MCULE-5554450813 ZINC190705 2-Amino-4-methyl-5-phenyl-3-thiophenecarbonitrile AKOS000511411 CTK4I5787 NSC-209020 [ Show all ]
Inchi Key	ALTJGNDYZQYJSC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H10N2S/c1-8-10(7-13)12(14)15-11(8)9-5-3-2-4-6-9/h2-6H,14H2,1H3
PubChem CID	308248
ChEMBL	CHEMBL565502
IUPHAR	N/A
BindingDB	50299479
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8568	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
8569	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877

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